Two Canadian women are the main suspects in the brutal murders of an Ontario couple at a luxurious resort near Cancun, a Mexican State Attorney spokesman confirmed Wednesday.

In a phone interview from his office in Chetumal, Mexico, Felipe Duran told The Canadian Press he could not confirm the women's identities nor media reports that were back in Canada.

Domenico Ianiero, a 59-year-old real estate agent, and his 55-year-old wife Annunziata, also known as Nancy, were found murdered in their hotel room on Monday. Their throats had been slashed, execution-style.

The luxurious all-inclusive Barcelo Maya hotel resort was to have been the site of the nuptials for their daughter on Tuesday.

But instead, it's become the scene of a messy murder investigation with possible international connections.

Interpol and RCMP officials in Canada told CP they have been in contact with local investigators, but declined to offer further information, saying it was a Mexican investigation.

Duran told the wire agency his office is in touch with the Canadian consulate, and that Canadian authorities would be called in to assist with extradition proceedings if necessary.

"The State Attorney is doing everything humanly possible to solve this isolated incident as quickly as possible," Duran said.

Family members became concerned when the couple failed to show up at a wedding party breakfast on Monday. Hotel security was called to check in on the couple.

When they arrived at the hotel room, they found the Ianieros lying in pools of blood.

Police told CTV's Scott Laurie that Domenico Ianiero was found in the bathroom, while Nancy was discovered in the bedroom.

It's believed nothing was stolen from the Ianieros' room, nor were there signs of forced entry.

"There was no sign of a robbery. Usually in this kind of crime, in this kind of setting, that's one of the first things that police might suspect," Laurie told Canada AM on Wednesday from Playa del Carmen. "But there's no evidence that happened in this case."

The couple from Woodbridge, Ont., north of Toronto, had four children, including twin girls, one of whom was to be married on Tuesday.

"They were wonderful, caring and just very kind people and we're all just really devastated," a sobbing niece of the couple, who refused to give her name, told CP on Wednesday.

"He was the head of our family, he kept us all together."

The couple's niece told CP that she is not sure when the wedding party will be returning home.

With the busy March break around the corner, tour operators are quick to remind Canadians that Mexico is still a safe vacation spot.

"It is a safe destination. We've seen a huge increase in passengers, Canadians especially, travelling to Mexico and haven't seen incidents like this," said Jonathan Carroll, president of itravel2000, told CTV News.

By Wednesday evening, Consular Affairs hadn't issued any new warnings for Canadians to avoid travel to Mexico.

With a report from CTV's Scott Laurie