Episode Guide

Give Peace a Chance

Give Peace a Chance

Season 6, Ep. 7

When Isaac, the hospital lab tech, has an inoperable tumor wrapped around his spine, he turns to Dr. Derek Shepherd to do the impossible, and Derek tests the Chief’s authority when Richard objects to moving forward with the risky surgery.

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I Saw What I Saw

I Saw What I Saw

Season 6, Ep. 6

After a burn victim unexpectedly dies in the midst of a chaotic ER, the Chief and board member Jennings interrogate the residents to find the culprit, as all the Mercy West and Seattle Grace resident defends their actions in an effort to save their jobs.

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Invasion

Invasion

Season 6, Ep. 5

The residents of Seattle Grace and Mercy West vie for surgeries and their careers as day one of the hospital merger begins. Meanwhile, Arizona stands by an enraged Callie when her father, Mr. Torres (guest star Hector Elizondo), employs a priest to help convince her to date men, and Izzie experiences the brunt of her new surgical competition.

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Tainted Obligation

Tainted Obligation

Season 6, Ep. 4

When Meredith and Lexie’s father, Thatcher (guest star Jeff Perry), returns to the hospital with a failed liver, it’s up to Meredith to save his life. Meanwhile, Izzie empathizes with a patient riddled with tumours, as Mark, annoyed with Cristina’s competitive zeal, tricks her into assisting on an unusual surgery.

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I Always Feel Like Somebody's Watchin' Me

I Always Feel Like Somebody's Watchin' Me

Season 6, Ep. 3

Several weeks after her near-death experience, a recovering Izzie returns to work. Meanwhile, nervous that there will be layoffs in the hospital in the wake of an announcement from the Chief, the Seattle Grace residents compete to survive the cuts, including Cristina, who attempts to work alongside Arizona in pediatrics. And Bailey and Alex's patient's already complex case is further complicated by her schizophrenic son

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Goodbye

Goodbye

Season 6, Ep. 2

Time has passed... Everyone is struggling after losing one of their own and are turning to any distraction they can find. Meredith and Derek seem to be consummating their marriage anywhere and everywhere, while Cristina and Owen have been instructed to abstain from sex by Dr. Wyatt.

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Good Mourning

Good Mourning

Season 6, Ep. 1

The hospital staff is left to deal with the aftermath of George's passing. Hitting the staff hard, they all find unique ways to get through the various stages of grief. George's mom returns, faced with the difficult task of deciding what to do with his organs.

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Now or Never (2)

Now or Never (2)

Season 5, Ep. 24

In the second part of the two hour season finale, George delivers stunning news to Bailey, sending shockwaves throughout the hospital, and Izzie's friends anxiously await her recovery from surgery. Meanwhile Bailey is surprisingly displeased after being accepted into the pediatric fellowship program, and the victim of a near-fatal traffic accident brings the talents of Seattle Grace's doctors together.

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Here's To Future Days (1)

Here's To Future Days (1)

Season 5, Ep. 23

In the first part of the two hour season finale, Izzie spends time with a fellow cancer patient and contemplates whether or not to undergo a risky surgery, as Mark is ready to take his relationship with Lexie to the next level and a patient makes Owen reassess his place at Seattle Grace.

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What a Difference a Day Makes

What a Difference a Day Makes

Season 5, Ep. 22

As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation ceremony, is admitted to the ER. Meanwhile, Izzie fears the worst when she begins experiencing familiar symptoms.

No Good at Saying Sorry (One More Chance)

No Good at Saying Sorry (One More Chance)

Season 5, Ep. 21

As preparations continue for Meredith and Derek's wedding, several residents must face the arrival of their parents at the hospital: Izzie's mother Robbie causes a stir when she pays a surprise visit, and Thatcher returns to make amends with Meredith and Lexie. The Chief clashes with Meredith over a controversial medical case.

Sweet Surrender

Sweet Surrender

Season 5, Ep. 20

Amidst a series of intense treatments, Izzie throws herself into Derek and Meredith's wedding plans, but the stress of her illness takes its toll on Alex, who freezes during surgery just as George begins to excel. Meanwhile, Callie's father arrives at Seattle Grace, but is less than pleased to meet his daughter's girlfriend. Owen seeks help to address his PTSD outbursts, and Bailey becomes emotionally attached to one of Arizona's young cancer patients.

Elevator Love Letter

Elevator Love Letter

Season 5, Ep. 19

While Derek prepares to perform his first surgery since his breakdown, Izzie must undergo one. Meanwhile, Owen has another PTSD episode, which injures Cristina, traumatizes both of them and throws their relationship into question.

Stand By Me

Stand By Me

Season 5, Ep. 17

While Mark attempts a face-transplant surgery, Meredith tries to get Derek to return to work after his fellow surgeons fail in their attempts. Meanwhile, Cristina finally gets a solo surgery, but she's more focused on the needs of her friends; and Izzie tries her best to keep her condition a secret.

I Will Follow You Into the Dark

I Will Follow You Into the Dark

Season 5, Ep. 17

Derek decides to quit after learning of a high mortality rate among his patients; Bailey and the chief continue to spar over her pediatrics fellowship until Adele (Loretta Devine) steps in; Izzie's interns find something disturbing about a Patient X.

An Honest Mistake

An Honest Mistake

Season 5, Ep. 16

Derek's confidence is shaken like never before as he faces off with Addison over what course is best for their dying pregnant patient; Cristina calls the abilities of a renown surgeon into question after she botches a standard procedure; and Bailey, who has decided to pursue a fellowship in Pediatrics, is appalled by the Chief's less-than-stellar recommendation letter.

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Before and After

Before and After

Season 5, Ep. 15

Addison, Naomi and Sam rush the ailing Archer to Seattle Grace and reunite with old friends Derek and Mark to help save his life; meanwhile, Izzie employs her fellow doctors in a medical game designed to help teach the interns, and Owen runs into a significant someone from his past.

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Beat Your Heart Out

Beat Your Heart Out

Season 5, Ep. 14

Now that Derek has the engagement ring, he searches for the perfect way to propose to Meredith, as Lexie demands that Mark go public with their relationship, and Bailey, encouraged by her work on recent cases and by Dr. Dixon, considers a new direction for her medical career.

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Stairway to Heaven

Stairway to Heaven

Season 5, Ep. 13

Bailey grows desperate as a patient's condition becomes more and more dire. Everyone in the hospital is stepping up to try to find the boy a new organ donor, including Meredith, who considers a death row patient's wish to die before execution. Meanwhile, an injury leaves Mark in a compromising position in the OR and Cristina awkwardly avoids Owen.

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Sympathy for the Devil

Sympathy for the Devil

Season 5, Ep. 12

Derek's mother, Carolyn (Tyne Daly), meets Meredith for the first time during a surprise visit to Seattle, and Mark tries to conceal his relationship with Lexie. Meanwhile, death-row inmate William (Eric Stoltz) wants to donate his organs to Bailey and Arizona's patient; and Owen and Cristina attempt to go on a first date.

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Wish You Were Here

Wish You Were Here

Season 5, Ep. 11

While Bailey teams with new pediatric surgeon Arizona Robbins (Jessica Capshaw ) to save a young patient near and dear to her heart, the arrival of a death-row inmate at the hospital angers Derek and further erodes Meredith and Cristina's friendship. Meanwhile, Callie and Sloan join forces to fight their respective attractions to Sadie and Lexie; and Izzie tells Alex that she has been seeing Denny (Jeffrey Dean Morgan).

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All By Myself

All By Myself

Season 5, Ep. 10

Cristina is awarded the first solo surgery among the residents, but she has to relinquish it and choose her replacement; Mark performs a cutting-edge procedure to restore a patient's speech, impressing Lexie in the process; and Callie can't figure out if Sadie (Melissa George) is flirting with her or just being friendly.

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In the Midnight Hour

In the Midnight Hour

Season 5, Ep. 9

A routine surgery goes horribly awry for Lexie and Sadie, so Meredith, Cristina and Bailey rush to assist them. Meanwhile, Owen and Derek treat a man who was injured while sleepwalking, and Mark comforts the man's daughter.

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These Ties That Bind

These Ties That Bind

Season 5, Ep. 8

Meredith's old friend Sadie (Melissa George) becomes an intern at Seattle Grace, but Meredith's other friends aren't exactly welcoming; new surgeon Virginia Dixon (Mary McDonnell) brings rules and order to the OR; and Lexie leads the interns in secretive, unorthodox surgical-training sessions.

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Rise Up

Rise Up

Season 5, Ep. 7

The Chief tells the residents that one of them will get a solo surgery, and a competitive frenzy ensues; Derek asks Bailey for advice when he feels that Cristina is coming between him and Meredith; Erica discovers a shocking connection between one of her residents and a longtime patient.

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