Investigators are looking for two pieces of blood-soaked bedding and information about bloody clothing and shoes in the disappearance of Orangeville nurse Sonia Varaschin who they believe is the victim of foul play.

In a media conference Friday morning, OPP Det. Insp. Mark Pritchard described the two bedding items as a beige, or cream-coloured fitted bedsheet and matching comforter. "I would expect the bedding to be blood-soaked," he added.

"It's quite apparent from our scene examination that when the culprit left the scene, he was covered in a significant amount of blood. The blood would be expected to be on both footwear and clothing," Pritchard revealed.

"It certainly appears that the culprit left the house in Sonia's car and then returned to downtown Orangeville with her car," Pritchard said, adding that police believe the person they are looking for is familiar with the Orangeville area.

Police say they are looking for one individual, who acted alone and is someone who knows or is familiar with Varaschin, but that she may not necessarily know.

Pritchard asked for the public's help, calling them "our eyes and ears" and asked that people come forward if they know of someone who has experienced a severe change in demeanor since Varaschin's disappearance, or someone who appears to be hiding from the public.

In a prepared statement read by Orangeville Police Chief Joseph Tomei, Varaschin's family thanked police, the community and media for all their assistance and asked for continued vigilance in finding, and getting justice for her.

Varaschin was last seen Sunday night and was reported missing on Monday morning when she failed to show up for work. That morning, her blood-splattered white Toyota Corolla was found abandoned in an Orangeville laneway with the trunk wide open. More blood was discovered nearby in the townhouse where she lived.

A massive police search continues in the rural area surrounding Orangeville, including mounted units from Toronto police and the OPP, with investigators working around the clock.

Orangeville police are urging anyone who may have seen Varaschin to immediately contact the dedicated tip line at 519-941-2522, ext. 2211. Tips can also be called in to Crime Stoppers at 1-800-222-TIPS, or emailed to police from the OPP Criminal Investigation Branch website for unsolved cases at www.opp.ca.