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Dr. Alain Beaudet looks on as Health Minister Leona Aglukkaq announces funding for MS treatment in the foyer of the House of Commons on Parliament Hill in Ottawa, Wednesday, June 29, 2011. (Adrian Wyld / THE CANADIAN PRESS) Liberation treatment MS patients rally for CCSVI, or chronic cerebrospinal venous insufficiency, in Toronto, Wednesday, May 05, 2010. Health Minister Leona Aglukkaq speaks during a press conference on funding clinical trials of a controversial MS therapy, Wednesday, June 29, 2011.

Feds OK funding for MS 'liberation therapy' trials

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CTV News Video

CTV National News: Avis Favaro on the funding
The federal government has said 'yes' to an in depth study of the so-called liberation therapy for multiple sclerosis.
CTV Edmonton: Serena Mah on the treatment
The federal government's health minister has given the green light to fund clinical trials of a controversial treatment for multiple sclerosis patients.
CTV Montreal: Cindy Sherwin on the funding
The federal government has announced funding for clinical trials on liberation therapy, a controversial way to treat MS.
CTV News Channel: Anna Delorme, MS patient
A multiple sclerosis patient says she noticed a number of improvements she experienced after she underwent the 'liberation therepy.'
CTV News Channel: Health Minister Leona Aglukkaq
In a press conference in Ottawa, Health Minister Leona Aglukkaq announces funding for clinical trials for the so-called 'liberation therapy' -- a controversial treatment for multiple sclerosis.

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Dr. Alain Beaudet looks on as Health Minister Leona Aglukkaq announces funding for MS treatment in the foyer of the House of Commons on Parliament Hill in Ottawa, Wednesday, June 29, 2011. (Adrian Wyld / THE CANADIAN PRESS) Liberation treatment MS patients rally for CCSVI, or chronic cerebrospinal venous insufficiency, in Toronto, Wednesday, May 05, 2010. Health Minister Leona Aglukkaq speaks during a press conference on funding clinical trials of a controversial MS therapy, Wednesday, June 29, 2011.

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Dr. Alain Beaudet looks on as Health Minister Leona Aglukkaq announces funding for MS treatment in the foyer of the House of Commons on Parliament Hill in Ottawa, Wednesday, June 29, 2011. (Adrian Wyld / THE CANADIAN PRESS)

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Date: Wed. Jun. 29 2011 10:28 PM ET

The federal government says it will fund clinical trials into the controversial multiple sclerosis treatment known as the "liberation therapy."

Federal Health Minister Leona Aglukkaq made the announcement Wednesday afternoon during a news conference on Parliament Hill.

Aglukkaq told reporters the government came to its decision after a scientific working group it convened last summer determined during a meeting on Tuesday that a Phase 1 and Phase 2 clinical trial should proceed.

"I have asked CIHR, the Canadian Institutes of Health Research, to establish the terms of reference for this clinical trial," Aglukkaq said. "And we are committed to launching an open and transparent call for proposals, and process applications, as quickly as possible."

The liberation treatment was developed by Italian physician Dr. Paolo Zamboni and is based on his theory that narrowed neck veins are behind MS symptoms.

The condition, chronic cerebrospinal venous insufficiency, or CCSVI, reduces blood flow and allows iron deposits to build up in the brain, Zamboni says.

The treatment he developed uses balloon angioplasty to unblock the veins in the hope of alleviating symptoms.

In an interview with CTV News, Zamboni called the government's announcement "fantastic news," saying Canadian MS patients "waited for this for a long time."

While Zamboni's research has demonstrated success with the treatment, recent clinical trials have concluded that CCSVI is not a primary cause of MS.

The controversy surrounding both the condition and the treatment has not deterred Canadian MS patients from rallying across the country over the last several months to call on both Ottawa and provincial governments to fund the treatment, which is not available in Canada. Many Canadians have had the procedure at medical clinics overseas.

Aglukkaq said the working group was established last August and tasked with reviewing the latest research and making its recommendation to government. The group met in November and again on Tuesday.

Dr. Alain Beaudet, president of the CIHR, said Wednesday that an analysis of all the research done on CCSVI so far suggested "a trend to an association between the greater prevalence of CCSVI in patients with MS than in healthy controls."

Beaudet said more results are needed, particularly from seven current studies, to strengthen the committee's conclusion.

"But, nonetheless, the committee felt that, on the basis of this preliminary evidence and what's published so far, that we should in parallel start already with a Phase 1-2 trial," he said.

Barrie, Ont. vascular surgeon Dr. Sandy McDonald has treated six patients with the liberation therapy, three of whom experienced a dramatic improvement in symptoms and two who experienced a moderate improvement.

McDonald said Zamboni's theory represents a "paradigm shift" in how MS is viewed. For decades, neurologists have approached MS as an autoimmune disorder, but the liberation treatment suggests that it is in fact a vascular disease.

McDonald said he was "ecstatic" when he heard the government's announcement, saying a randomized, controlled, double-armed trial -- during which doctors follow a group receiving the treatment and a group that does not -- will conclusively determine the treatment's effectiveness, as well as risks.

"We already know from trials done in the United States that the risks are very low, and we already know also from the trials out of the U.S. that it seems to be effective in improving the quality of life in many people," McDonald told CTV News Channel.

"But we shouldn't expect that it will be the panacea for all patients with MS. It may be a part of MS, and that's why we need the trials to prove it either is or isn't, and hopefully it proves it is and we can actually help patients have a better quality of life."

During her Wednesday news conference, Aglukkaq hailed MS patients and their families for their struggle with a disease that can lead to symptoms that include difficulty walking, vision problems, fatigue and weakness.

"It has been a moving experience to meet many of you and to hear from so many MS patients and their families who have shown tremendous courage in the face of such difficult illness," she said.

With reports from CTV medical specialist Avis Favaro and producer Elizabeth St. Philip

Comments are now closed for this story

robin hood
said
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Can't make money off of healthy people! This has got to be ticking someone off unless it's a trap!


Stu
said
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It's a good thing that they don't know whether it works or not. If it was proven to work there would be no way this government would support it. Harper doesn't believe in scientific facts.


Cara B, NS
said
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While I am very happy to hear that the government will be funding this research, it is somewhat disturbing to read comments relating to heart disease as something you must have brought on yourself. There is a very high genetic link to both heart disease and diabetes (which in itself tends to lead to heart disease) and anyone who has either of these diseases running through their families will tell you that there is no "choice" involved in whether you get it or not. It's great that MS sufferers may finally have some hope for effective treatment, but please, let's not turn this into a battle of one disease against another or a "blame game", saying people must have done something to deserve what they have. Let's just all hope that one day there will be cures for all these diseases .


Jim Lad
said
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We can only try. Let's see how it works. Best wishes to MS sufferers and their families.


Intelligent Liberal
said
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Harper is taking credit for an idea invented by the Liberal Party, that is why it is called LIBERALation treatment. Regardless, it is good news for MS sufferers, athough I'm surprised it works since I accidentally tried the Zamboni treatment years ago at a hockey rink and it really didn't feel very good.


Ian Ottawa
said
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First off I am glad the Harper Government is supporting this worthwhile research. Second I think that the reason the MS Society doesn't support the research is that they make tons of money in fundraising and a cure would force them as a Society to lose everything. Third and last point is the uneducated about heart illness. It does not always effect an unhealthy lifestyle. I had a heart attack and Never drank, smoked, ate poorly, was obese and in fact I taught fitness for over thirty years and was a competitive gymnast. Hereditary is a big factor.


Whiner - slayer
said
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I have followed this story from the start because a friend of mine has MS, and my former company supported the MSCC every year, so it piqued my interest. Having read endless articles, websites and comments from people below, all I can say about this group is what a bunch of ridiculous whiners. As soon as the theory came out - the call for research proposals went out right away and were announced and started within 6 months by the MSSC. An unheard of precedent. And BTW there were vascular specialists involved in the studies and the CIHR panel- why don’t you actually read the names and credentials of the authors don’t just repeat what other idiots say in blogs. Then a few months later, in August or Nov. the Gov. and the MS Society said that when the actual scientific evidence proved enough to support clinical trials they would support it. That's what they said and now that's what they did! All the conspiracy theorists can go sit on their thumbs now with all of their ridiculous accusations. OK so they've decided there are going to be clinical trials. No the Gov. should not give you back your money if you did it anyway. It is not a right to have experimental procedures in Canada. You just didn't listen and didn't want to wait. Other countries are not doing this procedure in their regular healthcare programs. Private clinics in other countries are happy to take your Canadian money to pay for this procedure because you want to have it done. They are not doing it for their own citizens because # 1 – it’s not standard therapy and even if it is proven beneficial will still take years to pass ethical protocols and clinical trials. #2 There is no public outcry for it-- people in other countries don't even know about CCSVI other than a passing story because it hasn't been blown up by the media as the "liberation theory" and declared the answer to all things MS. Only in this country do we have to make people out to be the bad guys because they are doing the intelligent and prudent thing to wait for scientific proof before backing a theory. All of those university educated and medical school graduates should just listen to Joe blow down the road who says they feel better and open up the public purse and forget their Oaths to “first do no harm” based on their word and not much more. That’s intelligent. Oh right I forgot education is a bad thing in this country –we don’t like those elite types. Right? Doing the right thing takes time – whining about it only takes a second. Maybe we can start getting liberation therapy at McDonalds in our fast-food and whining impatient culture.


Steve in Vancouver
said
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Take the billion dollars given to the CBC every year and sell their billions of dollars worth of real estate. Presto we have billions for medical research. lm glad to see the door open on providing attention to some real needs of Canadians. Put the money where there are real needs. We don't need to pay for phony culture and have it rob us of our tax dollars.


Charlotte
said
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Good for the Government and for people with MS and I am so glad they did all the research first and now can go ahead in the near future. Conservatives always do it the right way , what a boost for people with MS, Good Luck to all you people who benefit by this and all the best.


Dennis Jessome
said
0 0

While Watching CTV News this evening, I was overjoyed to hear the Announcement ,The Canadian Government is going ahead with the clinical trials on all CCVSI and MS . Now there is a chance of Hope, for all Canadian Citizens , with this dreadful disease, for a better Quality of life, with their Families , Thank you Canada.


Jazz
said
0 0

Very Happy for those MS patients looking for relief. I am glad that our Government is pitching in to not only help them but to help those studying this disease learn more and possibly one day solve this problem. Sorry to 'Fed Up' that he has heart issues and that the Billions of dollars already given to the Heart and Stroke Foundation hasn't helped. To those nailing this guy, he may not have this trouble because of his own circumstances so lighten up in assuming he is some lazy fat oaf.


Liz
said
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@Fed Up...what about...???
I have had MS the last decade, and it is has not been easy. I am sorry that you suffer with heart disease, but balking at research funding for another disease that you don't have is not the answer.


Alex
said
0 0

The Liberation treatment relieves symptoms of the disease, it has taken people from a wheel chair, to doing jumping jacks 3 days later. It is a minor surgery. that takes basically a glorified ultrasound to diagnose narrowed veins. There have been people die from the surgery however it is very rare. some people notice no or little improvement. For some this can be the difference between being bed ridden and not. To get a medical procedure of any kind you have to sign a waiver of liability, why not let us see the facts, make a decision, sign the waiver and be done with it. I for 1 have PPMS, my loss of abilities increases everyday. I would like to have the surgery while I can still walk, I know the risks, and I want to take them.


raj
said
0 0

Well, I am pleased that those that want this, don't have to leave the country. OTOH, the MS society itself doesn't seem to endorse this procedure. I am for anyone getting what they need to make life easier


Glenn C
said
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Finally ms. L something that you have actually contributed to!


NS
said
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Good choice, both morally and financially.


Dianne of Mtl
said
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Why is everyone assuming that "fed up" is an overweight smoker? And yes Heart Disease is a killer while MS is not. But help for anyone with any illness is good news Mr fed up. Hopefully it will be your turn next. I have to say that I think the only reason the gov't is acting is because of the pressure from the public. Kudos to every yelling voice - keep yelling. By the way, I am an MS sufferer. I am also a 2-time cancer survivor and I would love to hear some good news in that area too. Lets keep nagging the government to do what we elected them to do!


Nina Khehra
said
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I am FED Up with being forced to live with symptoms of MS, while the government decides what to do with Zamboni's Liberation procedure. Why could MS patients understand how it worked, while highly qualified doctors could not? Neurologists were finally forced to think outside of their comfort zone, and they did not appreciate what they saw. I was forced to leave Canada to be Liberated in Newport beach, California this January. Will the government re-imburse me for my trouble???


Prof. Pye Chartt
said
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Another example of the "evil" things that "evil" Conservatives are capable of, and, in particular, Harper & Company. (Wonderful news.)


Denise B. from Edmonton
said
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It is about time! But I wonder if the trials will be as skewed as the CIHR's 'expert' panel that poo-pooed the notion of CCSVI in the first place that did not contain any vascular experts! I can only hope that they are conducted with integrity! I never used to be so sceptical and cynical until this fiasco! Whether or not this has anything to do with causing or contributing to MS it can improve the quality of life of people with MS and we should start working to perfect the procedure and minimize the risk of restenosis - I would happily volunteer to be a guinea pig for this cause! Unlike most cases of heart disease, "fed up", this illness strikes people in their youth or in their prime and the victims have done little of nothing to contribute to the development of it. It is wonderful to have hope that the future may see a marked reduction in the decline toward disability and death for MS sufferers. It may not even be too late for me even though I have been unable to work for two years! We may actually be able to hope that Canada may have Health Care again instead of just sick care!


Linda
said
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If the Federal Govn't would take the results of MS patients that have had to leave their country to have the procedure and apply it to the clinical studies they are now going to do...they would be way ahead with the info and get the procedure approved for MS patients to help manage their disease. This information has been paid for out of pocket by Canadians and it should be compiled and used to lead the way into the research and save valuable time.


LYNNE HEAL
said
0 0

Canada has deserved this for a very long time now. I have paid attention from UK hopefully UK and other countries will also start as well


Susan
said
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Wonderful! I think is great! We can use our tax money that can help me and us that have MS.


NuerosSuck!
said
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It's about bloody time!


Math Guy
said
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To "Fed up": I wonder what fraction of MS patients would trade their quality of life for that of an overweight smoker with heart disease (noting that a small fraction of people with heart disease have not made such poor life choices)? Perhaps research should be directed towards diseases with unknown causes...


somebody's mom
said
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This is a TREATMENT for MS patients no one ever said it was a cure - but if it offers relief why should people have to leave the country to have it done. It is about time Canada started to do something - but how long is it going to take before the treatment is ACTUALLY being done here?


SAM
said
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I'm so happy for every MS sufferer who would like this procedure available to them! I hope it works well.


Diane
said
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@fed up - your handle is the problem. "FED UP". There are numerous natural remedies for improving our heart health and reducing threats through prudent food management. Sorry you feel aggrieved but there are choices to make which can make a difference even now.


Good move eh!
said
0 0

As a Canadian I believe this is a good move and a better expenditure of taxpayers money than some old left wing think tank that clamors for annual funding for useless intellectual pursuits. Embracing a potential cure or treatment for MS is important to the many who suffer from this disease. Good for Canada.


fed up? really??
said
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So sorry the government can't immediately help your cause there fed up!! How about show gratitude that the government is at least funding the develepment for a cure for any disease. We could simply stop funding for your heart pills and or any treatment and simply let you die. Can't cure the whole world at once now can we? Now if only we could cure selfishness?


Kelly
said
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No one ever said it was the primary cause or a final cure for MS. However, glasses don't cure poor eyesight, advil doesn't cure headaches and hearing aids don't cure hearing loss, but they sure help and are commonly used in this country! I am glad the end to discrimination against people with MS is near!


Pauline Wilson
said
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Well, I am so pleased that Canada has finally stepped to the plate. I leave with my daughter for California in 10 days for the treatment, it's unfortunate it has taken so long. However, with her steady decline it must be now. But at least it's a blessing knowing if she has to have a second or third proceedure done at least she can have it done at home. Thank you Ms. Aglukkaq for your determination in following this through. This is truly a blessing for all Canadian MS patients. Happy Canada Day!


Tom [Kingston]
said
0 0

"fed up" when a comparable breakthrough in research is proposed and demonstrated for heart patients, I will love to support research by the Federal Gov't to fund it. Until then hope for one or better yet a cure.


Tom [Kingston]
said
0 0

Finally Canada is listening. It might not help 100% of MS patients, however even if it helps a fraction it is worth it in my book and I do not mind my tax dollars going into positive life altering research to support and aid MS patients. At times we need to take risks to acquire results or knowledge that will help others. Good on you Canada.


Al
said
0 0

Good - it should be studied to get at the truth; I am glad that the Feds are going to proceed.


fed up
said
0 0

What about heart disease that kills more Canadians every year than any other disease?. Many Canadians have heart disease that cannot be cured and I am one of them, the pills I take are useless and I live from one day to another and many thousands of Canadians are in my situation and nobody is helping us at all.


Denise
said
0 0

Glad to hear it. If there is any chance that this very common surgery will provide a better quality of life for even some MS sufferers, then clinical trials should proceed. I suspect it will work for some, not so much for others.


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