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Smoking marijuana helps reduce pain, trial shows
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CTV.ca News Staff
Date: Mon. Aug. 30 2010 9:17 PM ET
Though many who suffer chronic pain will tell you that smoking pot can help dull the pain, there has been little hard medical research into whether it really is effective.
Now, a new randomized, placebo-controlled clinical trial, appearing in the Canadian Medical Association Journal, shows that marijuana really can bring pain relief and improved sleep to those in chronic pain.
Dr. Mark Ware, director of research at the Alan Edwards Pain Management Unit of the McGill University Health Centre, led a team who studied the pain-relieving effects of smoking cannabis in 21 people with "chronic neuropathic pain": those who had constant nerve pain, caused by trauma or surgery.
All had suffered the pain for at least three months, had failed to get effective relief from other medications, and reported an average weekly pain intensity score greater than 4 on a 10-point scale.
To ensure that the participants couldn't tell who was smoking real marijuana and who was smoking a placebo, the patients were given a special pipe and 25-milligram capsules of a substance to be lit and inhaled once. The capsules contained either 2.5 per cent, 6 per cent or 9.4 per cent tetrahydrocannabinol (THC), which is the active ingredient in marijuana. The placebo pill contained no THC.
They smoked the pipe three times daily for five days in each cycle, followed by a nine-day period without marijuana. They continued this over two months, rotating through all four strengths of THC.
The researchers found that those smoking the tabs with the highest potency, 9.4 per cent, saw their average pain "significantly reduced" compared with those smoking the placebo. The patients also reported improvements in sleep quality and anxiety.
Because the dosages were fairly small compared to what "recreational" pot smokers would receive, most participants said they didn't get "high" from the drug; "euphoria" was reported on only three occasions.
The researchers note that off the one puff, the blood levels of THC in the study participants reached only about 45 nanograms per milliliter, whereas most pot smokers would see levels reach 100 ng/mL and higher.
"We used a small dose for two reasons," Ware explained to CTV News Channel. "One was to reduce the likely effect on the lung; it was a smoked product after all, so we wanted minimize the possible effects on the lung and respiratory track.
"The second reason was to minimize the possible psychoactive effects. We were not using this as a way to get people high but to try to ameliorate a very devastating symptom of chronic neuropathic pain."
Some of the patients did report side effects, including dizziness, numbness and a burning sensation in areas of neuropathic pain.
The researchers note that while cannabis has been used to treat pain since the third millennium B.C., the pain-relieving effects of the drug remain controversial in the medical community. Further study on whether the drug really works is needed, the researchers said, given that at least 10 per cent of patients with chronic non-cancer pain and other conditions have tried using marijuana to relieve pain.
The researchers say they would like to see larger and longer studies on marijuana, using higher potencies and flexible dosing to see if pain levels can be reduced even further.
"What I hope this study will do is highlight for patients and physicians that cannibinoids -- the active ingredients in marijuana -- are a legitimate contribution to pain management and should be considered as one option when you are trying to treat chronic pain," Ware said.
In an accompanying editorial, Dr. Henry J. McQuay of Oxford University, notes that the results are important in light of the fact that patients interested in the pain relief offered by medical marijuana have seen only a "trickle" of evidence to prove the claims that the drug works.
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Comments are now closed for this story
Yvonne
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Jordan
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So what?
Jerry in Calgary
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Dr. Richard K.
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Prof. Pye Chartt
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Dan
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This is supposed to be a free country and I don't need the nanny-state to look after me let alone imposing restrictions that put public safety at risk by funneling billions of dollars to organized crime.
I am a university educated professional and the government should stay out of my business and certainly not be imposing regulations that put my safety as a consumer and as a citizen at risk by pushing most of an enormous and very successful industry (that will never be destroyed regardless of ideological desires) into the hands of organized crime.
Daniel From Toronto
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andre
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Logic dictates it was the milk that caused his schizophrenia.
D. Keyes
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Doug # BC
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moi
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Harper is the prime minister that allowed me to smoke beautiful, pure mj, grown in a lab in SK for my MS. because I can control my pain, I'm back to work. I work thankfully in a creative field that encourages my quirkiness ;)
Harper does not fill our jails with potheads. Please, get a clue.
the gangs that control the distribution of the beautiful plant are the problem. So is US policy!
we will decriminalize and eventually legalize mj. Studies like this only help the cause. there are THOUSANDS of Canucks smoking/growing/selling legally!
Do the responsible thing, stop using it
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Dave
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eric strader
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PAUL
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3Doves
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JM
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USMC DISABLED
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until something happens to them.then you'll see how they're thinking changes. i can see you people rolling your eyes.i forgot nothing can happen to you, you're invincible.i thought that way once. do you think something made in a lab is better for you then a natural weed?
Always awake when the rest of the world is asleep
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Rebos
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I love how people have the perception that people who smoke are lazy no good bums who are on welfare.... that is liquor or crack my friends....
And to anyone who isn't suffering from an illness that might require this as a form of relief... stop talking. You have absolutely no idea what some of the people are going through on a daily basis.
Yes, the drug is harmful to your body, however if your in agonizing pain on a daily basis, you are probably going to 'risk' the chance of lung cancer or any side effect known to occur.
Glen
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This will go on and on. No amount of studies that will be done in the decades ahead will amount to anything. This is just a dangling fishing lure!
Follow the money, and you will find the reason why marijuana is illegal.
Long-Time Smoker
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I have been smoking it for over 30 years on a regular basis, I have a good job with lots of responsibilities and you wouldn't even know I smoked (and no mental illness). I hate it when people make us feel like we are such bad people! There is more than likely a lot of people around you who smoke it, so I think you are the clueless ones! Non-smokers try to find any excuse to stop something that is natural.
Live and let live!
Damon
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Damon
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IRespectMostSoldiersJustNotYou
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Do you understand the dangers of most prescriptioon painkillers? They too are abused, and can actually kill you, just like alcohol. POT CANNOT KILL YOU. It has never killed anyone. Period. It's simply not possible, you would have to smoke 5 times your body weight in 20 minutes, which isnt even humanly possible. You say it should be policed like alcohol or prescription drugs? Which one is it? Cause you sure don't need a prescription to go to the liquor store and buy enough booze to kill you.
Erik
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Dave in Downtown Newington
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Jessica
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PS- one of the first studies that showed Marijuana killed brain cells, was done on monkeys who where literrally suffocated on marijuana smoke for minutes at a time. The study was fixed this way so they could say conclusively that it killed brain cells, when they couldn't legitamitely prove it. Any half wit can tell the brain damage resulted from lack of oxygen, not pot smoke.
Prof. Pye Chartt
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cabowabo
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Azaelea
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Or should I take Lyrica which makes me lose my balance and my memory to the point I didn't remember what day it was and leave the stove till the pot cooked dry and caught fire as well as causing weight gain because I can't walk properly because I'm so dizzy or should I use the morphine which has been prescribed for me and when I've been taking it long enough I go onto methadone so I don't get totally addicted.
Curious how those of you who don't have a clue about chronic nerve pain can be so quick to judge!
Dawn
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Amanda
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Malcolm Chevrier
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Eric L
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Eric L
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CYL
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RWR
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Eric L
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Ron from Georgetown
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PVT
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Albertaboy111
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Canadian Soldier
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OXYCODENE ANYONE?
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suffering in Idaho
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And euphoria being portrayed as a negative side effect is ludicrous!
There is no link between cannabis and mental illness. Some people are obsessive by nature and that is a recognized fact in the mental health industry. Pot makes you feel good and feeling good is something people obsess over. I've been a toker for 40 years and have known thousands of users and none of then were psyco from their pot use. Now, when you throw booze into the mix, it it a completely different story. Pot with booze makes you a worse driver than booze alone, but pot alone makes you a safer driver. Pot with cigarettes causes more lung ailments than cigarettes alone, but pot alone is actually therapeutic for lung ailments. These are facts discovered in clinical studies. I'm not surprised about booze and pot, but it's a shocker that pot alone is actually beneficial to lung cancer patients.
JJ
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TJ
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ts
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Ken
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Peter
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No. MJ is neither a hallucinogen nor a mind-altering drug.
"Therefore, since it alters the perception of the user and makes the person euphoric, then the user thinks that the pain is relieved."
No, like codine and morphine MJ is psycho-active. That is to say it tells the mind to quit receiving pain signals. If you feel that's 'fake' pain relief then by all means feel free to refuse anesthetic before your next operation since it works essentially the same way.
"Marijuana is a depressant and is not a stimulant. Stimulants like alcohol, caffeine makes you active and aggressive."
Alcohol is not a stimulant, it's a depressant.
tij
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Marijuana is a depressant and is not a stimulant. Stimulants like alcohol, caffeine makes you active and aggressive. Marijuana makes you sleepy and stoned to the point where the user stares blankly into whatever catches his/her attention.
I heard that cocaine, LSD, and meth will take away all your pain also and will make you happy. The pot thing is really BIG news. Duh!
JB in Ontario
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Jennifer Wilson
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For those of you who think that pot makes people "crazy" take a look in the mirror after you have had a drink or two or three or four. I'd rather hand with the people on pot than alchohol. Pot doesn't change your mind set and doesn't make you feel invincible. Pot won't make you get into your car and kill someone, pot won't give you the courage to you beat on your mate or someone who looks at you the wrong way. Come on, seriously give your head a shake.
Robert Branning
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Tom
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Angel
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of course it helps, and its not as addictive as the rest of the pharms made from opiates!
My mom at 75 is on more drugs than pot could shake a leaf at! Benzos plus t3s plus sleeping pills and gaba, and other sedatives plus the dr knows she is an alchy......tell me a joint would not be better than all that crap in her system and teh sides she gets omg.....pot has no sides and for many is NOT addictive. Yes there are some who should not and cannot smoke it but hey some of us cannot eat peppers or are allergic to pollen while otehrs not.....we are all different in our chemical balance and this can help some balance themselves adn not haev to be on oxy, perks....geez humans are sooo behind!
whatstheharm
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dram2500
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Wayne
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Wayne
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Steve
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Marijuana does not cause lung cancer. I challenge you to find any evidence to back up your claim. No one has ever gotten lung cancer from marijuana use alone. Also, marijuana does not have to be smoked to recieve it's benefits. Marijuana can be vaporised which is much healthier for the lungs. It can also be cooked and put in various forms of food and that works too. I've even seen medical marijuana dispensaries that have it spray form were you just squirt it on your tounge and that works as well.
Nathalie
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Recovered Pot Smoker
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Nanner67
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David
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Prof. Pye Chartt
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Jillian Galloway
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According to the ONDCP, two-thirds of the Mexican drug cartel's money comes from selling marijuana in the U.S., and they protect this cash flow by brutally torturing, murdering and dismembering thousands of innocent people.
If we can STOP people using marijuana then we need to do so now, but if we can't then we need to legalize the production and sale of marijuana to adults with after-tax prices set too low for the cartels to match. One way or the other, we have to force the cartels out of the marijuana market and eliminate their highly lucrative marijuana incomes - no business can withstand the loss of two-thirds of its revenue!
To date, the cartels have amassed more than 100,000 "foot soldiers" and operate in 230 U.S. cities, and the longer they're able to exploit the prohibition the more powerful they'll get and the more our own personal security is put in jeopardy.
Mark
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william30035@earthlink.net
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James
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chel in the Peg
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Tod
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Ryley (SK)
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Peter
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Craig in Calgary
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Denny, Manchester
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About 6 years ago i persuaded her to give pot a go as nothing else was working (it was about 5 weeks after having her gall bladder removed because of the pain meds she was on). Guess what, immediate releif!! Were talking pain levels dropping to a 4-5. She was able to sleep properly for the first time in years. She got a job as an editor of a political health magazine and was able to reduce the benefits she was on by working and contributing to society again.
She still smokes it now, her doctors all agree that pot is the best thing for her by far and another guess what, she has not gone mad and she has not developed cancer, although she has said it wouldn't be such a bad thing as at least then there is an end to the pain.
We need to stop being so close minded and have proper research into this plant as it could hold the key to improving so many peoples quality of life!
penny
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Spiltbongwater
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James miramichi nb
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thetruth1028@yahoo.com
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Richard in New Brunswick
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Paul ,Edmonton
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